This course is intended for Chemistry, Biochemistry, and Biology majors and counts as an elective for the Biochemistry, Chemistry, and Biology majors. Course lecture will focus on discussions of the biochemical aspects of neurodegenerative diseases, addiction, and poisons, such as the roles of metal ions and non-covalent interactions in protein folding and function. The course involves extensive reading and discussion of primary literature with a strong focus on data interpretation and experimental design.
- Explain mechanisms of protein-misfolding and other neurological disorders.
- Apply knowledge from introductory biochemistry coursework to follow biochemical disease pathways.
- Review findings from high-level primary literature at forefront of current knowledge.
- Discuss ethical concerns related to disease diagnosis, prevention, and treatment.
- Compare different disease pathways and effects.
- Discover and summarize results from primary literature.
- Analyze experimentally collected biochemical data.
- Debate validity and impact of scientific reports with contrasting viewpoints.
- Prepare presentations based on in-depth understanding of biochemical literature.
- Design an independent biochemical research proposal.