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CHEM 231 Organic Chemistry I

The first semester of a comprehensive course in organic chemistry. This course covers structure and nomenclature, bonding theory, reaction mechanisms, stereochemistry, reaction kinetics and thermodynamics, instrument methods [e.g. NMR, IR, MS] and the syntheses and reactions of various functional groups of organic compounds. Molecular modeling software is used to assist in visualizing structures and reaction mechanisms, and in the interpretation of various spectra. The lab portion of the course introduces the techniques, specialized equipment, instrumental methods and safety procedures common in an organic lab setting. Students get hands-on experience with the instrumentation and equipment. Intended for chemistry, biochemistry, and biology majors as well as chemistry minors.

Prerequisites

5 Undergraduate credits

Effective May 6, 2026 to present

Learning outcomes

General

  • Correctly translate among compound names and various representations of organic compound structures such as skeletal, Lewis, condensed and 3-D structures, giving valid resonance structures when appropriate
  • Correlate structural features (including geometric shape and stereochemistry) of organic molecules with observed physical properties
  • Identify acid-base chemistries utilizing curved-arrow mechanisms
  • Identify various functional groups within complex molecules and the relevant chemistries each functional group will undergo (including alkenes, alkynes, alcohols, epoxides, ethers, aldehydes and ketones)
  • Employ data from MS, IR, and NMR to identify unknown compounds; develop an understanding of how each of these analytical techniques work
  • Identify factors contributing to alkyl substitution and elimination mechanisms
  • Perform laboratory techniques including chromatography, extraction, distillation, recrystallization, and organic synthesis safely and accurately.
  • Understand and consistently apply principles of scientific ethics and academic integrity.
  • Use instrumentation including FTIR, GCMS, and NMR to support compound structure.
  • Develop observations into formal lab reports, using proper laboratory, data analysis, and scientific writing conventions.